Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients

Islam Ebeid; Walaa Farid; Ashraf Ahmed; Neveen Samy

doi:doi:10.11648/j.ccr.20200404.18

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Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients

Islam Ebeid, Walaa Farid, Ashraf Ahmed, Neveen Samy

Published in Cardiology and Cardiovascular Research (Volume 4, Issue 4)

Received: 9 January 2020 Accepted: 27 January 2020 Published: 16 December 2020

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Abstract

Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease (CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.

Published in	Cardiology and Cardiovascular Research (Volume 4, Issue 4)
DOI	10.11648/j.ccr.20200404.18
Page(s)	215-219
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Coronary Artery Disease, Risk Factors, Angiography, Young Adults

References

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[2]	Shah, Nadim, et al. Myocardial infarction in the “young”: risk factors, presentation, management and prognosis. Heart, Lung and Circulation, 2016, 25.10: 955-960.‏
[3]	Yang, Junjie, et al. Risk Factors and Outcomes of Very Young Adults Who Experience Myocardial Infarction: The Partners YOUNG-MI Registry. The American journal of medicine, 2019; 6: 169-173.
[4]	Pradhan, Ravi R., et al. Acute myocardial infarction in a young adult treated successfully with primary percutaneous transluminal coronary angioplasty. European Journal of Biomedical, 2018, 5.1: 799-802.‏
[5]	Vernon, Stephen T., et al. Increasing proportion of ST elevation myocardial infarction patients with coronary atherosclerosis poorly explained by standard modifiable risk factors. European journal of preventive cardiology, 2017, 24.17: 1824-1830.‏
[6]	Gebhard, Catherine, et al. Impact of age and sex on left ventricular function determined by coronary computed tomographic angiography: results from the prospective multicentre CONFIRM study. European Heart Journal-Cardiovascular Imaging, 2017, 18.9: 990-1000.‏
[7]	R Nakazato, R Arsanjani, et al. Age-related risk of major adverse cardiac event risk and coronary artery disease extent and severity by coronary CT angiography: results from 15 187 patients from the International Multisite CONFIRM Study. Eur Heart J Cardiovasc Imaging. 2014 May; 15 (5): 586–594.
[8]	Abed, Mona A.; ESHAH, Nidal F.; MOSER, Debra K. Risk profile of myocardial infarction in young versus older adults. Heart & Lung, 2018, 47.3: 226-230.‏
[9]	Maino, Alberto, et al. Recurrence and mortality in young women with myocardial infarction or ischemic stroke: long-term follow-up of the Risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) study. JAMA internal medicine, 2016, 176.1: 134-136.‏
[10]	Bajaj S, Shamoon F, et al. Acute ST-segment elevation myocardial infarction in young adults: who is at risk? Coron Artery Dis. 2011; 22 (4): 238–44.
[11]	Desai, Arpan P.; BHAGARHATTA, Rajeev. Localization of Angina Related Artery By Admission ECG in Unstable Angina and Nstemi Patients. Journal of Hypertension and Cardiology, 2016, 2.1: 10.‏
[12]	Nichols M, Townsend N, et al. Cardiovascular disease in Europe 2014: epidemiological update. Eur Heart J 2014; 35: 2929 [PMID: 25381246.
[13]	Choi J, Daskalopoulou SS, et al. Sex- and gender-related risk factor burdenin patients with premature acute coronary syndrome. Can J Cardiol 2014; 30: 109-117.
[14]	Aggarwal A, Aggarwal S, Sharma V. Cardiovascular Risk Factors in Young Patients of Coronary Artery Disease: Differences over a Decade. J Cardiovasc Thorac Res 2014; 6: 169-173.
[15]	Wadkar A, Sathe A, et al: Clinical & angiographic profile of young patients (<40 years) with acute coronary syndrome. Journal of indian college of cardiology 2014; 4, 95-100.
[16]	Smyth, Andrew, et al. Response by Smyth et al to Letters Regarding Article,“Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction: The INTERHEART Study”. Circulation, 2017, 135.10: e644-e645.‏
[17]	Schoenenberger AW, Radovanovic D, et al: Acute coronary syndromes in young patients: presentation, treatment and outcome. Int J Cardiol. 2011; 148 (3): 300-4.

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APA Style

Islam Ebeid, Walaa Farid, Ashraf Ahmed, Neveen Samy. (2020). Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiology and Cardiovascular Research, 4(4), 215-219. https://doi.org/10.11648/j.ccr.20200404.18

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ACS Style

Islam Ebeid; Walaa Farid; Ashraf Ahmed; Neveen Samy. Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiol. Cardiovasc. Res. 2020, 4(4), 215-219. doi: 10.11648/j.ccr.20200404.18

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AMA Style

Islam Ebeid, Walaa Farid, Ashraf Ahmed, Neveen Samy. Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiol Cardiovasc Res. 2020;4(4):215-219. doi: 10.11648/j.ccr.20200404.18

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@article{10.11648/j.ccr.20200404.18,
  author = {Islam Ebeid and Walaa Farid and Ashraf Ahmed and Neveen Samy},
  title = {Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients},
  journal = {Cardiology and Cardiovascular Research},
  volume = {4},
  number = {4},
  pages = {215-219},
  doi = {10.11648/j.ccr.20200404.18},
  url = {https://doi.org/10.11648/j.ccr.20200404.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20200404.18},
  abstract = {Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease (CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.},
 year = {2020}
}

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TY  - JOUR
T1  - Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients
AU  - Islam Ebeid
AU  - Walaa Farid
AU  - Ashraf Ahmed
AU  - Neveen Samy
Y1  - 2020/12/16
PY  - 2020
N1  - https://doi.org/10.11648/j.ccr.20200404.18
DO  - 10.11648/j.ccr.20200404.18
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 215
EP  - 219
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20200404.18
AB  - Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease (CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.
VL  - 4
IS  - 4
ER  -

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Author Information

Islam Ebeid

National Heart Institute, Cairo, Egypt
Walaa Farid

Cardiology Department, Menoufia University, Shebin Elkom, Egypt
Ashraf Ahmed

National Heart Institute, Cairo, Egypt
Neveen Samy

Cardiology Department, Menoufia University, Shebin Elkom, Egypt

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Plain Text BibTeX RIS

APA Style

Islam Ebeid, Walaa Farid, Ashraf Ahmed, Neveen Samy. (2020). Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiology and Cardiovascular Research, 4(4), 215-219. https://doi.org/10.11648/j.ccr.20200404.18

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ACS Style

Islam Ebeid; Walaa Farid; Ashraf Ahmed; Neveen Samy. Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiol. Cardiovasc. Res. 2020, 4(4), 215-219. doi: 10.11648/j.ccr.20200404.18

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AMA Style

Islam Ebeid, Walaa Farid, Ashraf Ahmed, Neveen Samy. Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients. Cardiol Cardiovasc Res. 2020;4(4):215-219. doi: 10.11648/j.ccr.20200404.18

Copy | Download

@article{10.11648/j.ccr.20200404.18,
  author = {Islam Ebeid and Walaa Farid and Ashraf Ahmed and Neveen Samy},
  title = {Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients},
  journal = {Cardiology and Cardiovascular Research},
  volume = {4},
  number = {4},
  pages = {215-219},
  doi = {10.11648/j.ccr.20200404.18},
  url = {https://doi.org/10.11648/j.ccr.20200404.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20200404.18},
  abstract = {Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease (CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Pattern of Risk Factors and Angiographic Features of Coronary Artery Disease in a Sample of Young Egyptian Patients
AU  - Islam Ebeid
AU  - Walaa Farid
AU  - Ashraf Ahmed
AU  - Neveen Samy
Y1  - 2020/12/16
PY  - 2020
N1  - https://doi.org/10.11648/j.ccr.20200404.18
DO  - 10.11648/j.ccr.20200404.18
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 215
EP  - 219
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20200404.18
AB  - Objectives: this study aimed to study the pattern of risk factors & angiographic features of CAD in young patient aged < 45 in comparison with older patients in a sample of Egyptian patients. Background: Egypt is one of the developing countries where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity of young adults (aged < 45 years) with coronary artery disease (CAD). Methods: Our study was a prospective, cross sectional study conducted at multicenter hospitals included 300 patients with coronary artery disease (CAD), group I comprised of one hundred patients aged < 45 years old and group II comprised of two hundred patients ≥ 45 years old who underwent coronary angiography at National Heart Institute, Menoufia university hospital from October 2018 to April 2019. Results: Smoking and positive family history were significantly higher in group I with age (<45 years) than group II (≥45years). HTN, DM, obesity were significantly higher in group II with age (≥45years) than group I (<45 years). The most common clinical presentation was STEMI were significantly higher in group I than group II & SCAD was in the second order with significantly higher in group II than in group I. One vessel and two vessel disease were most prominent in group I versus group II while MVD was most prominent in group II versus group I with significant P value 0.010. Type A and B lesions were the most common types of lesion in group I, while type C lesion was more common in group II than group I, with significant P value (0.019). Calcified, bifurcational and ostial lesions were most prominent in group II with highly significant P value (<0.001) in calcified lesions. Conclusion: Primordial prevention about smoking cessation and life style modification in cutting down obesity will be important epidemiological tool. Awareness on this topic, importance of golden hour and early diagnosis and treatment will have huge economic impact as sizeable number of patients present late.
VL  - 4
IS  - 4
ER  -

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