Volume 3, Issue 2, June 2019, Page: 27-30
Familial Apical Hypertrophic Cardiomyopathy in a Young Adult: A Rare Occasion for Making Precise Diagnostic in a Low Income Country
Sylvie Ndongo Amougou, Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon; Department of Internal Medicine, Yaoundé University Teaching Hospital, Yaoundé, Cameroon
Helles Murielle Lema, Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon
Mazou Ngou Temgoua, Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon
Ngam Mary Engonwei, Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon
Samuel Kingue, Department of Internal Medicine, Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon; Department of Internal Medicine, General Hospital of Yaoundé, Yaoundé, Cameroon
Received: Apr. 14, 2019;       Accepted: May 23, 2019;       Published: Jun. 11, 2019
DOI: 10.11648/j.ccr.20190302.12      View  162      Downloads  18
Abstract
Hypertrophic Cardiomyopathy is a genetic disorder with asymmetric left ventricular hypertrophy. In a low income country it is sometimes difficult to do global checkup and precise diagnosis in suspected patients. We present a case of apical hypertrophic cardiomyopathy with MYBPC3 mutation in a young Cameroonian. A 36 years old man with no cardiovascular risk factors, presents with a progressive chest pain on exertion. The physical examination was normal. The resting electrocardiography showed inverted T waves in anterior, lateral and inferior leads. Treadmill electrocardiography and Coronarograpy were normal. A transthoracic cardiac ultrasound showed hypertrophy of 168 mm in the apical segment, the systolic function and the regional wall motion of the left ventricle were normal. We concluded of hypertrophic cardiomyopathy with abnormality in the myosin binding protein C (MYBPC3) found on genetic analysis. A screening cardiac ultrasound was realized in the patient’s family and the son was found to have septal hypertrophy. Strict follow-ups were organized for the patient and his son. Familial Hypertrophic Cardiomyopathy is a rare disease in cardiology; the precise diagnosis requires complex exams which are sometimes unavailable in low income countries. This case was a special one with all necessary investigations giving the possibility to organize follow-ups for patient and related family member to prevent sudden death.
Keywords
Familial Hypertrophic Cardiomyopathy, Young Adult, Diagnosis, Low Income Country
To cite this article
Sylvie Ndongo Amougou, Helles Murielle Lema, Mazou Ngou Temgoua, Ngam Mary Engonwei, Samuel Kingue, Familial Apical Hypertrophic Cardiomyopathy in a Young Adult: A Rare Occasion for Making Precise Diagnostic in a Low Income Country, Cardiology and Cardiovascular Research. Vol. 3, No. 2, 2019, pp. 27-30. doi: 10.11648/j.ccr.20190302.12
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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