Volume 3, Issue 2, June 2019, Page: 31-36
Intraprocedural Stent Thrombosis: Case Series of a Rare Complication Managed Successfully
Nikesh Jain, Jaslok Hospital and Research Centre, Mumbai, India
Nilesh Tawade, Narayana Institute of Cardiac Sciences, Bangalore, India
Nihar Mehta, Jaslok Hospital and Research Centre, Mumbai, India
Ajit Desai, Jaslok Hospital and Research Centre, Mumbai, India
Ashwin Mehta, Jaslok Hospital and Research Centre, Mumbai, India
Received: May 1, 2019;       Accepted: Jun. 10, 2019;       Published: Jun. 26, 2019
DOI: 10.11648/j.ccr.20190302.13      View  270      Downloads  40
Intra-procedural stent thrombosis (IPST) is defined as the development of occlusive or non-occlusive new thrombus in or adjacent to a recently implanted stent before the PCI procedure is completed. The frequency of occurrence currently ranges between 0.5 – 1.7% of all PCI procedures and it seems to be considerably reduced with newer drug eluting stents and improved techniques. The occurrence of IPST is relatively rare, even in ACS patients, and is related strongly to clinical presentation and procedural factors (e.g., anticoagulation regimen, lesion type, presence of thrombus at baseline, stent under expansion and edge dissection etc.) than to baseline demographic characteristics. Imaging modalities like IVUS or OCT can prevent as well as identify the underlying cause for IPST. IPST not only decreases success rate of PCI but is also associated with higher rates of slow flow or no reflow, distal embolization and side branch closure. It is also associated with higher mortality, myocardial infarction, ischemia driven revascularisation and stent thrombosis on follow up. IPST can be managed immediately in cath lab and involves use of GP2b3a inhibitors, optimising stent apposition by repeat balloon dilatation, use of imaging to identify the cause and accordingly corrective measures to be taken. Rarely emergency CABG may be required if underlying cause cannot be corrected. Prevention is the key. IPST can be prevented by using newer anti-platelets, use of GP2b3a inhibitors especially in presence of ACS or high thrombus load, preparing the lesion well before stenting, use of atherectomy devices when needed, appropriate stent size selection and use of imaging modalities in complex lesions to optimise stent selection and apposition. We describe three cases of the intra procedural stent thrombosis under different clinical scenarios and its management.
Intraprocedural Stent Thrombosis, Intravascular Imaging, Newer Anti Platelets
To cite this article
Nikesh Jain, Nilesh Tawade, Nihar Mehta, Ajit Desai, Ashwin Mehta, Intraprocedural Stent Thrombosis: Case Series of a Rare Complication Managed Successfully, Cardiology and Cardiovascular Research. Vol. 3, No. 2, 2019, pp. 31-36. doi: 10.11648/j.ccr.20190302.13
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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