Volume 3, Issue 3, September 2019, Page: 71-79
Fragmented QRS Complex as a Predictor of High Risk in Acute Coronary Syndrome
Hanan Ibrahim Radwan, Cardiology Department, Zagazig University, Zagazig, Egypt
Kamal Saad Mansour, Cardiology Department, Zagazig University, Zagazig, Egypt
Mohammed Mustafa Al-Daydamony, Cardiology Department, Zagazig University, Zagazig, Egypt
Reema Saed Mohammed, Cardiology Department, Al-Margab University, Alkhoms, Libya
Received: Aug. 17, 2019;       Accepted: Sep. 4, 2019;       Published: Sep. 23, 2019
DOI: 10.11648/j.ccr.20190303.16      View  453      Downloads  105
Background: To detect the potential in hospital prognostic value of fQRS complex in patients with acute coronary syndrome (ACS) & investigate whether FQRS complex can be used to distinguish patients with early NSTEMI from those with unstable angina. Methods: It included 150 patients with acute NSTEMI and unstable angina. All patients were subjected to Grace score calculation, ECG to detect ischemic changes and detect presence or absent of fQRS, transthoracic echo to detect LV ejection fraction and recording in-hospital outcome. Results: Patients with fQRS have significant higher Killip class>2, higher troponin &CKMB levels, higher grace score, increased LVEDD & LVESD and significantly lower LVEF%. LVEF is significantly lower among patients with fQRS than patients with not fQRS in NSTEMI patients while there is no significant difference of LVEF % between both groups in unstable angina patients. There is significant association between fQRS and higher prevalence of NSTEMI and higher incidence of heart failure, arrhythmia and bad outcome. By multivariate analysis, NSTEMI (p =0.003) and high HR (p =0.004) and fragmented QRS (p =0.00) were the only significant predictors for bad outcome. FQRS have the ability to diagnose NSTEMI in 47.9% of cases, fQRs can truly exclude NSTEMI in 72.7% of case. Conclusion: Among patients with ACS, the presence of fQRS was associated with an increase incidence of complication, worse outcome, larger LV dimensions, and lower LVEF. The presence of fQRS in acute coronary syndrome patients could predict the presence of NSTEMI with fair diagnostic value.
ACS (NSTEMI, Unstable Angina), Fragmented QRS Complex, Hospital Outcome
To cite this article
Hanan Ibrahim Radwan, Kamal Saad Mansour, Mohammed Mustafa Al-Daydamony, Reema Saed Mohammed, Fragmented QRS Complex as a Predictor of High Risk in Acute Coronary Syndrome, Cardiology and Cardiovascular Research. Vol. 3, No. 3, 2019, pp. 71-79. doi: 10.11648/j.ccr.20190303.16
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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