Volume 4, Issue 2, June 2020, Page: 34-46
The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients
Ehab El-Hefny, Faculty of Medicine, Al Azhar University, Cairo, Egypt
Abdel Mageed Tag El-Din, Faculty of Medicine, Al Azhar University, Cairo, Egypt
Ayman Sadek, Faculty of Medicine, Al Azhar University, Cairo, Egypt
Eslam Abbas, Oncocardiology Department, Dar El Salam Cancer Center, Cairo, Egypt
Received: Feb. 28, 2020;       Accepted: Mar. 16, 2020;       Published: Apr. 21, 2020
DOI: 10.11648/j.ccr.20200402.12      View  298      Downloads  87
Background: Silent myocardial ischemia is a major component of the total ischemic burden for patients with ischemic heart disease. The disease is more prevalent in diabetic patients than their peers, and early detection of the high-risk group would play an integral role in the prevention of sudden cardiovascular accidents that are common in these patients. Methods: A prospective cohort study including asymptomatic 53 diabetic patients with diabetic retinopathy who suffer no ischemic cardiac symptoms was conducted. The presence and degree of diabetic retinopathy were evidenced using fundus examination and optical coherence tomography. All the enrolled patients underwent stress-resting 99mTc SestaMIBI myocardial perfusion scintigraphy to detect the ischemic burden. The relation between diabetic retinopathy and silent myocardial ischemia was stratified using statistical analysis. Results: A total of 13 diabetic patients (24.5%) have silent myocardial ischemia in the form of regional myocardial perfusion abnormalities. The strongest predictors of abnormal tests were the presence of moderate to severe retinopathy, comorbid hypertension and diabetic duration for more than 10 years. Conclusion: Silent myocardial ischemia affects one in four asymptomatic diabetic patients suffering from diabetic retinopathy. The presence of comorbid risk factors such as high-grade retinopathy, hypertension and/or long diabetic duration surge the incidence and considered additional predictors of the disease.
Diabetic Retinopathy, Silent Myocardial Ischemia, Optical Coherence Tomography, Myocardial Perfusion Imaging
To cite this article
Ehab El-Hefny, Abdel Mageed Tag El-Din, Ayman Sadek, Eslam Abbas, The Degree of Retinopathy Correlates with the Presence of Silent Myocardial Ischemia in Diabetic Patients, Cardiology and Cardiovascular Research. Vol. 4, No. 2, 2020, pp. 34-46. doi: 10.11648/j.ccr.20200402.12
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This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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