Volume 4, Issue 3, September 2020, Page: 85-91
An Evaluation of the Frequency and Severity of Erectile Dysfunction in Hypertensive Married Men Compared with Normotensive Married Men
Kabirul Hasan Bin Rakib, Department of Medicine, Mugda Medical College Hospital, Mugda, Dhaka, Bangladesh
Afroja Alam, Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
Md. Atikur Rahman, OSD-Directorate General of Health Services (DGHS), Mohakhali, Dhaka, Bangladesh
Nazim Al Azad, Department of Internal Medicine, Mugda Medical College Hospital, Mugda, Dhaka, Bangladesh
Akm Habibullah Bahar, Department of Medicine, 250 Bedded General Hospital, Tangail, Bangladesh
Nazmul Hoque Munna, Department of Neurology, Mugda Medical College Hospital, Mugda, Dhaka, Bangladesh
Rabeya Bosri, Department of Gynae & Obs., Mugda Medical College Hospital, Dhaka, Bangladesh
Shaheen Lipika Quayum, Department of Pharmacology, Popular Medical College, Dhaka, Bangladesh
Md. Abul Kalam Azad, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
Received: Apr. 22, 2020;       Accepted: May 21, 2020;       Published: Jun. 9, 2020
DOI: 10.11648/j.ccr.20200403.12      View  60      Downloads  39
Background: Erectile dysfunction (ED) exerts a major burden on the quality of life of the patients and their sexual partners. It has been identified as an independent risk factor for cardiovascular disease. Hypertension is a well-established risk factor for ED. Both hypertension and erectile dysfunction has age dependent relationship. Objective: To evaluate the frequency and severity of erectile dysfunction in hypertensive married men compared with normotensive married men of similar demographic characteristics attending a tertiary care hospital of Bangladesh during the period from June 2017 to March, 2018. Methodology: This cross-sectional comparative study includes 75 hypertensive and 75 normotensive young and middle-aged married men (31–59 years) those visited our outpatient clinic. From them, 75 patients had hypertension and 75 were normotensive. Erectile dysfunction was evaluated with pre validated Bengali version of the International Index of Erectile Function (IIEF-5) questionnaire. Results: Erectile dysfunction (ED) was found in 61.3% of patients with hypertension compared with 37.3% of normotensive subjects. ED is more common and more severe among hypertensive patients than normotensive counterparts. Hypertension duration, hypertension severity and age were found positively correlated with erectile dysfunction. Taking regular medication and control of BP gave positive influence upon erectile status. No association was found between ED and smoking but a weak negative correlation of increased body mass index (BMI) and decreased ED was found in both hypertensive and normotensive group. Conclusion: Hypertensive patients present with erectile dysfunction more frequently than age matched normotensive individuals. As erectile dysfunction is a matter of embarrassment, doctors should be motivated to discuss such issue. Control of blood pressure seems to confer good influence upon the prevalence of erectile status. We need further studies to authenticate such observation and to unveil other risk factors of ED in our country and to go for appropriate management.
Erectile Dysfunction (ED), Cardiovascular, Hypertension, Body Mass Index (BMI)
To cite this article
Kabirul Hasan Bin Rakib, Afroja Alam, Md. Atikur Rahman, Nazim Al Azad, Akm Habibullah Bahar, Nazmul Hoque Munna, Rabeya Bosri, Shaheen Lipika Quayum, Md. Abul Kalam Azad, An Evaluation of the Frequency and Severity of Erectile Dysfunction in Hypertensive Married Men Compared with Normotensive Married Men, Cardiology and Cardiovascular Research. Vol. 4, No. 3, 2020, pp. 85-91. doi: 10.11648/j.ccr.20200403.12
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This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cordero, A., Bertomeu Martínez, V., Mazón, P., Fácila, L., Bertomeu□González, V., Conthe, P., et al 2010. Erectile dysfunction in high risk hypertensive patients treated with beta blockade agents. Cardiovascular Therapeutics 28 (1), pp. 15-22.
Caro, J. L. L., Vidal, J. V. L., Roca, M. A., Bravo, C. P., Vicente, J. A., Ferrario, C. M. et al., 2001. Sexual dysfunction in hypertensive patients treated with losartan. The American Journal of the Medical Sciences 321 (5), pp. 336-41.
Bate, A., Lindquist, M., Edwards, I. R., Olsson, S., Orre, R., Lansner, A. and De Freitas, R. M., 1998. A Bayesian neural network method for adverse drug reaction signal generation. European Journal of Clinical Pharmacology 54 (4), pp. 315-21.
Della, CA, Pfiffner, D, Meier, B and Hess OM., 2003 Sexual activity in hypertensive men. Journal of human Hypertension. 17 (8), pp. 515–21.
Kifor, I., Williams, G. H., Vickers, M. A., Sullivan, M. P., Jodbert, P. and Dluhy, R. G., 1997. Tissue angiotensin II as a modulator of erectile function. I. Angiotensin peptide content, secretion and effects in the corpus cavernosum. The Journal of Urology 157 (5), pp. 1920-25.
WHO. 2017. Life expectancy report of Bangladesh. 2017, Geneva. World Health Organization, Available from www. world life expectancy.com/country – health- profile/Bangladesh.
Doumas, M., Tsakiris, A., Douma, S., Grigorakis, A., Papadopoulos, A., Hounta, A., Tsiodras, S., Dimitriou, D. and Giamarellou, H., 2006. Factors affecting the increased prevalence of erectile dysfunction in Greek hypertensive compared with normotensive subjects. Journal of Andrology 27 (3), pp. 469-77.
Doumas, M. and Douma, S., 2006. The effect of antihypertensive drugs on erectile function: a proposed management algorithm. The Journal of Clinical Hypertension 8 (5), pp. 359-63.
Laumann, E. O., Paik, A. and Rosen, R. C., 1999. Lecture 6: the epidemiology of erectile dysfunction: results from the National Health and Social Life Survey. International Journal of Impotence Research 11 ( suppl 1), pp. S60-S64.
Sullivan, M. E., Keoghane, S. R. and Miller, M. A. W., 2001. Vascular risk factors and erectile dysfunction. British Journal of Urology International, 87 (9), pp. 838-45.
Sasayama, S., Ishii, N., Ishikura, F., Kamijima, G., Ogawa, S., Kanmatsuse, K., Kimoto, Y., Sakuma, I., Nonogi, H., Matsumori, A. and Yamamoto, Y., 2003. Men's Health Study. Circulation Journal 67 (8), pp. 656-59.
Watts, G. F., Chew, K. K. and Stuckey, B. G. 2007. The erectile–endothelial dysfunction nexus: new opportunities for cardiovascular risk prevention. Nature Reviews Cardiology 4 (5), p. 263.
Montorsi, P., Ravagnani, P. M., Galli, S., Salonia, A., Briganti, A., Werba, J. P. and Montorsi, F., 2006. Association between erectile dysfunction and coronary artery disease: matching the right target with the right test in the right patient. European Urology, 50 (4), pp. 721-31.
Burchardt, M., Burchardt, T., Baer, L., Kiss, A. J., Pawar, R. V., Shabsigh, A., De La Taille, A., Hayek, O. R. and Shabsigh, R., 2000. Hypertension is associated with severe erectile dysfunction. The Journal of Urology 164 (4), pp. 1188-91.
Chun J, and Carson CC., 2001. Physician-patient dialogue and clinical evaluation of erectile dysfunction. Urologic Clinic of North America 28, pp. 249–58.
Rosen, R. C., Cappelleri, J. C., Smith, M. D., Lipsky, J. and Pena, B. M., 1999. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. International Journal of Impotence Research, 11 (6), pp. 319-26.
Burchardt, M., Burchardt, T., Anastasiadis, A. G., Kiss, A. J., Shabsigh, A., de La Taille, A., Pawar, R. V., Baer, L. and Shabsigh, R., 2001. Erectile dysfunction is a marker for cardiovascular complications and psychological functioning in men with hypertension. International journal of impotence research 13 (5), p. 276.
Jensen, J., Lendorf, A., Stimpel, H., Frost, J., Ibsen, H. and Rosenkilde, P., 1999. The prevalence and etiology of impotence in 101 male hypertensive outpatients. American Journal of Hypertension, 12 (3), pp. 271-75.
Mittawae, B., El-Nashaar, A. R., Fouda, A., Magdy, M. and Shamloul, R., 2006. Incidence of erectile dysfunction in 800 hypertensive patients: a multicenter Egyptian national study. Urology 67 (3), pp. 575-78.
Korenman, S. G., 1998. New insights into erectile dysfunction: a practical approach. The American Journal of Medicine, 105 (2), pp. 135-44.
Feldman, H. A., Goldstein, I., Hatzichristou, D. G., Krane, R. J. and McKinlay, J. B., 1994. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. The Journal of Urology 151 (1), pp. 54-61.
Prisant, L. M., Carr, A. A., Bottini, P. B., Solursh, D. S. and Solursh, L. P., 1994. Sexual dysfunction with antihypertensive drugs. Archives of Internal Medicine 154 (7), pp. 730-36.
Grimm, R. H., Grandits, G. A., Prineas, R. J., McDonald, R. H., Lewis, C. E., Flack, J. M., et al 1997. Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Hypertension 29 (1), pp. 8-14.
Kushiro, T., Takahashi, A., Saito, F., Otsuka, Y., Soma, M., Kurihara, T., Satomura, A., Saito, T. and Kanmatsuse, K., 2005. Erectile dysfunction and its influence on quality of life in patients with essential hypertension. American Journal of Hypertension 18 (3), pp. 427-30.
Cao, S., Yin, X., Wang, Y., Zhou, H., Song, F. and Lu, Z., 2013. Smoking and risk of erectile dysfunction: systematic review of observational studies with meta-analysis. PLoS One 8 (4), p. e60443.
Dorey, G., 2001. Is smoking a cause of erectile dysfunction? A literature review. British Journal of Nursing 10 (7), pp. 455-65.
Feldman, H. A., Johannes, C. B., Derby, C. A., Kleinman, K. P., Mohr, B. A., Araujo, A. B. and McKinlay, J. B., 2000. Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Preventive medicine 30 (4), pp. 328-38.
Johannes, C. B., Araujo, A. B., Feldman, H. A., Derby, C. A., Kleinman, K. P. and McKinlay, J. B., 2000. Incidence of erectile dysfunction in men 40 to 69 years old: longitudinal results from the Massachusetts male aging study. The Journal of Urology 163 (2), pp. 460-63.
Moreira Júnior, E. D., Bestane, W. J., Bartolo, E. B. and Fittipaldi, J. A. S., 2002. Prevalence and determinants of erectile dysfunction in Santos, southeastern Brazil. Sao Paulo Medical Journal 120 (2), pp. 49-54.
Bacon, C. G., Mittleman, M. A., Kawachi, I., Giovannucci, E., Glasser, D. B. and Rimm, E. B., 2003. Sexual function in men older than 50 years of age: results from the health professional’s follow-up study. Annals of Internal Medicine 139 (3), pp. 161-68
Vallancien, G., Emberton, M., Harving, N. and van Moorselaar, R. J. A., 2003. Sexual dysfunction in 1,274 European men suffering from lower urinary tract symptoms. The Journal of Urology 169 (6), pp. 2257-61.
Chung WS, Park YY, Kwon SW., 1997. The impact of aging on penile hemodynamics in normal responders to pharmacological injection: a doppler sonographic study. The Journal of Urology., 157 pp. 229–31.
Derby, C. A., Mohr, B. A., Goldstein, I., Feldman, H. A., Johannes, C. B. and McKinlay, J. B., 2000. Modifiable risk factors and erectile dysfunction: can lifestyle changes modify risk. Urology 56 (2), pp. 302-6.
Chitaley, K., Kupelian, V., Subak, L. and Wessells, H., 2009. Diabetes, obesity and erectile dysfunction: field overview and research priorities. The Journal of Urology 182 (6), pp. S45-S50.
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