Cardiology and Cardiovascular Research

Volume 5, Issue 3, September 2021

  • Quantification of Coronary Inflammation Using Fat Attenuation Index (FAI) in Indians: A Retrospective Study

    Atul Kapoor, Aprajita Kapoor, Goldaa Mahajan

    Issue: Volume 5, Issue 3, September 2021
    Pages: 129-134
    Received: 9 June 2021
    Accepted: 23 June 2021
    Published: 30 June 2021
    Abstract: Background: Asian Indians have the highest prevalence (11%) of coronary artery risk worldwide compared to all other races. So far no quantifiable risk factor has been shown to explain such a high prevalence. Fat attenuation index (FAI) using CT coronary angiography (CTCA) has been recently used to demonstrate coronary perivascular inflammation and ... Show More
  • Relationship Between Geometry and Ventricular Filling Pressures in Non-Diabetic Hypertensive Patients

    Alejandro Suarez

    Issue: Volume 5, Issue 3, September 2021
    Pages: 135-140
    Received: 24 May 2021
    Accepted: 16 June 2021
    Published: 9 July 2021
    Abstract: Hypertension and obesity make changes in the heart that are known as remodeling and diastolic dysfunction. These changes are the beginning of a later sistolic heart failure. Objectives Searching for the relation between geometry and ventricular function in hypertensive non diabetic and obese patients. 68 women and 20 men were evaluated by doppler- ... Show More
  • Novel Animal Model for Ventricular Ejection Fraction Measured by MRI

    Josefino Tunac, Frederick Valeriote, Joseph Media, Robert Knight

    Issue: Volume 5, Issue 3, September 2021
    Pages: 141-146
    Received: 18 August 2021
    Accepted: 30 August 2021
    Published: 11 September 2021
    Abstract: Aim: The objective of this study is to evaluate an animal model, herein called the Tunac Arterial Plaque (TAP) mouse as a model for reduced left ventricle ejection fraction (LVEF). Traditional mouse models involve genetically modified or surgically altered animals, whereas the TAP model is a wild mouse (C57Bl/6 strain) fed with a high fat diet and ... Show More
  • Assessment of Right Ventricular Function in Patients with Cor Pulmonale: Strain Imaging Study

    Mohamed Elnoamany, Tarek Khalil, Ghada Soltan, Naglaa Fahim, Mohamed Omran

    Issue: Volume 5, Issue 3, September 2021
    Pages: 147-152
    Received: 20 August 2021
    Accepted: 1 September 2021
    Published: 14 September 2021
    Abstract: Background: Cor pulmonale is one of the leading causes of heart failure. Speckle tracking echocardiography is a potential modality for evaluation of systolic and diastolic functions, myocardial mechanics and other cardiac pathophysiological processes. Objective: This study aims to assess the right ventricular (RV) function in patients with cor pulm... Show More
  • Myocardial Infarction with Non-obstructive Coronary Arteries (MINOCA): A Case Report and Review of the Literature

    Jie Chen, Wenjie Liang, Mei Wei, Mingqi Zheng, Gang Liu, Guoping Ma

    Issue: Volume 5, Issue 3, September 2021
    Pages: 153-156
    Received: 19 August 2021
    Accepted: 3 September 2021
    Published: 15 September 2021
    Abstract: Background: About 5-10% of all myocardial infarction patients undergoing diagnostic coronary angiography for typical chest pain have no significant coronary stenosis (stenosis severity <50%). We classified these patients as myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA), which is characterized by both the diagnostic criteria of myocardial infarction and no significant coronary stenosis (stenosis severity <50%). The pathophysiology of MINOCA is multifactorial. Potential underlying mechanisms of MINOCA include coronary causes such as coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli, and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies; and noncardiac causes, for example, pulmonary embolism. Early secondary prophylaxis with drugs including statins and renin-angiotensin-aldosterone system inhibitors may be beneficial to prognosis. Objective: To report a case of MINOCA, analyze its clinical manifestations, imaging and related treatment, and improve the understanding of clinicians on MINOCA. Met... Show More